NEW YORK (AP) " The Cleveland Indians set the bar for Yankee Stadium's new record book Saturday, scoring 14 runs in the second inning of a 22-4 victory.
Asdrubal Cabrera hit a grand slam and an RBI single in the second as the Indians chased struggling starter Chien-Ming Wang (0-3) and set several marks that could stand for a while at New York's swanky new home.
Mark DeRosa and Shin Soo-Choo each hit a three-run homer, Travis Hafner, Grady Sizemore and Victor Martinez had solo shots and manager Eric Wedge earned his 500th victory.
It was the most runs for the Indians since they beat New York 22-0 on Aug. 31, 2004, at the old Yankee Stadium. The 22 runs also tied the Yankees' record for most allowed in a home game.
Fausto Carmona (1-2) was the beneficiary of the Indians' big day at the plate, working six innings in his first victory of the season. He allowed four runs and six hits.
Tigers 2, Mariners 0
SEATTLE (AP) " Edwin Jackson baffled the Mariners again, allowing five hits while working into the eighth inning for Detroit.
Jackson (1-0), who beat the Mariners twice last season and has a career ERA of 0.40 against them, struck out six and walked one in 7 2-3 innings.
He outpitched Seattle's Erik Bedard (1-1), who allowed two runs and seven hits in six innings. He struck out eight in his first start at Safeco since be beat Detroit on July 4.
Fernando Rodney pitched the ninth to pick up his third save.
Brandon Inge singled in a run in the sixth and another run scored on right fielder Ichiro Suzuki's throwing error.
Blue Jays 4, Athletics 2
TORONTO (AP) " Lyle Overbay hit a two-out, two-run homer off Dan Giese in the 12th inning for Toronto.
After a two-out walk to Jose Bautista, Overbay hit a towering drive to center off Giese (0-1), who was called up from Triple-A earlier in the day.
Right-hander Jason Frasor (2-0) got two outs for the win for Toronto. Blue Jays starter Brian Tallet gave up two runs " one earned " and four hits in 5 1-3 innings. He walked one and struck out one.
Trevor Cahill allowed two runs and five hits in 5 1-3 innings, walking five for Oakland.
White Sox 8, Rays 3
ST. PETERSBURG, Fla. (AP) " Paul Konerko homered and drove in three runs, Mark Buehrle pitched effectively into the seventh inning for Chicago.
Buehrle (2-0) gave up eight hits, three walks and struck out five in 6 2-3 innings.
Carlos Quentin also homered for Chicago, which has won five of seven.
Tampa Bay left-hander Scott Kazmir (2-1) failed in his bid to open the season with three straight wins, giving up six runs and five hits in four-plus innings.
Twins 9, Angels 2
MINNEAPOLIS (AP) " Jason Kubel had his second consecutive four-hit game and Minnesota cruised to a victory.
Kubel's two-run double off Kevin Jepsen (0-2) was the big hit of Minnesota's five-run fifth. He also scored three runs a night after finishing off his cycle with a go-ahead grand slam in Minnesota's 11-9 victory on Friday.
Kevin Slowey (2-0) worked deep in counts for much of his seven innings, but his lone blemish was Torii Hunter's two-run homer in the second inning.
Red Sox 6, Orioles 4
BOSTON (AP) " Kevin Youkilis fell a triple short of the cycle and drove in four runs for Boston.
Youkilis went 4-for-5 with a three-run homer and two doubles as the Red Sox won their third straight after starting 2-6. Baltimore dropped its third consecutive game following a 6-2 start.
Mike Lowell had a pair of hits and an RBI for Boston.
Youkilis hit a three-run drive into the seats above the Green Monster off starter Adam Eaton (0-2) to put Boston ahead 4-0.
Josh Beckett (2-1) struggled with his control at times in his six innings.
Royals 2, Rangers 0
ARLINGTON, Texas (AP) " Zack Greinke did not allow a run for his third straight start, pitching a seven-hitter for his first career shutout.
Greinke (3-0) prevailed in a matchup of aces who started the day with the two lowest ERAs in the AL " Greinke at 0.00 and Texas' Kevin Millwood at 0.64.
Greinke has thrown 34 consecutive scoreless innings. He struck out a season-high 10 and didn't issue a walk in his fourth career complete game in 106 starts.
Billy Butler had an RBI double in the sixth and Miguel Olivo hit a solo homer in the seventh for the Royals.
Millwood (1-1) allowed two runs and five hits in nine innings for his 18th career complete game.