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FILE - In this Nov. 2, 2010 file photo, Rep. Shelley Berkley, D-Nev., gives a thumbs up after winning re-election to Congress during the Nevada State Democratic election night party in Las Vegas. Berkley's campaign announced Thursday, April 14, 2011 that she will run for the U.S. Senate seat now held by embattled Nevada Republican John Ensign, who is retiring. (AP Photo/Eric Jamison, File)

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